| Date | Rencontre | Comp. | Fiche | ||
| 17 juil. | Manchester United | 3-1 | Celtic Glasgow | AMC | |
| 22 juil. | Philadelphia Union | 0-1 | Manchester United | AMC | |
| 26 juil. | Kansas City Wizards | 2-1 | Manchester United | AMC | |
| 29 juil. | MLS All-Stars | 2-5 | Manchester United | AMC | |
| 31 juil. | Chivas | 3-2 | Manchester United | AMC | |
| 4 août | Eire XI | 1-7 | Manchester United | AMC | |
| 8 août | Manchester United | 3-1 | Chelsea FC | CS | |
| 16 août | Manchester United | 3-0 | Newcastle United | EPL JI |  |
| 22 août | Fulham FC | 2-2 | Manchester United | EPL J2 | |
| 28 août | Manchester United | 3-0 | West Ham United | EPL J3 | |
| 11 sept. | Everton FC | 13:45 | Manchester United | EPL J4 | |
| 14 sept. | Manchester United | 20:45 | Glasgow Rangers | C1 1 | |
| 19 sept. | Manchester United | 14:30 | Liverpool FC | EPL J5 | |
| 26 sept. | Bolton Wanderers | 13:00 | Manchester United | EPL J6 | |
| 29 sept. | FC Valence | 20:45 | Manchester United | C1 1 | |
| 2 oct. | Sunderland AFC | 16:00 | Manchester United | EPL J7 | |
| 16 oct. | Manchester United | 16:00 | West Bromwich | EPL J8 | |
| 20 oct. | Manchester United | 20:45 | Bursaspor | C1 1 | |
| 24 oct. | Stoke City | 14:30 | Manchester United | EPL J9 | |
| 30 oct. | Manchester United | 18:30 | Tottenham Hotspur | EPL J10 | |
| 2 nov. | Bursaspor | 20:45 | Manchester United | C1 1 | |
| 6 nov. | Manchester United | 16:00 | Wolverhampton | EPL J11 | |
| 10 nov. | Manchester City | 21:00 | Manchester United | EPL J12 | |
| 13 nov. | Aston Villa | 13:45 | Manchester United | EPL J13 | |
| 20 nov. | Manchester United | 16:00 | Wigan Athletic | EPL J14 | |
| 24 nov. | Glasgow Rangers | 20:45 | Manchester United | C1 1 | |
| 27 nov. | Manchester United | 16:00 | Blackburn Rovers | EPL J15 | |
| 4 déc. | Blackpool | 16:00 | Manchester United | EPL J16 | |
| 7 déc. | Manchester United | 20:45 | FC Valence | C1 1 | |
| 11 déc. | Manchester United | 16:00 | Arsenal FC | EPL J17 | |
| 18 déc. | Chelsea FC | 16:00 | Manchester United | EPL J18 | |
| 26 déc. | Manchester United | 16:00 | Sunderland AFC | EPL J19 | |
| 28 déc. | Birmingham City | 16:00 | Manchester United | EPL J20 | |
| 1er janv. | West Bromwich | 16:00 | Manchester United | EPL J21 | |
| 4 janv. | Manchester United | 21:00 | Stoke City | EPL J22 | |
| 15 janv. | Tottenham Hotspur | 16:00 | Manchester United | EPL J23 | |
| 22 janv. | Manchester United | 16:00 | Birmingham City | EPL J24 | |
| 1er fév. | Manchester United | 21:00 | Aston Villa | EPL J25 | |
| 5 fév. | Wolverhampton | 16:00 | Manchester United | EPL J26 | |
| 12 fév. | Manchester United | 15:00 | Manchester City | EPL J27 | |
| 26 fév. | Wigan Athletic | 16:00 | Manchester United | EPL J28 | |
| 5 mars | Liverpool FC | 16:00 | Manchester United | EPL J29 | |
| 19 mars | Manchester United | 16:00 | Bolton Wanderers | EPL J30 | |
| 2 avril | West Ham United | 16:00 | Manchester United | EPL J31 | |
| 9 avril | Manchester United | 16:00 | Fulham FC | EPL J32 | |
| 16 avril | Newcastle United | 16:00 | Manchester United | EPL J33 | |
| 23 avril | Manchester United | 16:00 | Everton FC | EPL J34 | |
| 30 avril | Arsenal FC | 16:00 | Manchester United | EPL J35 | |
| 7 mai | Manchester United | 16:00 | Chelsea FC | EPL J36 | |
| 14 mai | Blackburn Rovers | 16:00 | Manchester United | EPL J37 | |
| 22 mai | Manchester United | 17:00 | Blackpool | EPL J38 | |
